题目：Relation between Blood Pressure and Pulse Wave Velocity for Human Arteries

时间：2019年4月17日 15:00-16:00

地点：80足球直播吧 振华会议室

主办方：机械系统与振动国家重点实验室 专家讲坛

报告人简介：

黄永刚，固体力学家。美国西北大学冠名讲席教授。美国工程院院士，欧洲科学院院士，
欧洲科学与艺术院院士，中国科学院外籍院士。

黄永刚教授的主要学术成就包括: 1）可延展无机电子器件：基于力学原理创立了可延展无机电子器件的分形互联导线、硅应变隔离设计等新概念，提出了定量化设计理论和制备方法，实现超过300%的器件延展率，极大拓展了器件应用范围，开发了电子眼相机、表皮电子等多种全新器件，相关专利被工业界用于研发生产多种柔性健康监测产品。2）基于微观机制的应变梯度理论：创立基于微观机制的应变梯度理论体系，成功解释纳米压痕实验尺度效应，成为该类实验的技术标准，被来自54个国家几百所大学、研究机构和公司所采用并广泛应用于微纳米力学性能测定。上述成果奠定并拓展了现代力学研究前沿，产生广泛而重要的学术影响。

黄永刚为我国力学学科和柔性电子学科的发展做出了重要贡献。为国内培养和输送了一批固体力学和柔性电子科研骨干，在美国培养的17名中国博士生和博士后已回国工作，含1名973首席、3名杰青、6名优青。与同国内学者联合发表380余篇SCI论文，含《Science》6篇及其子刊3篇，《Nature》1篇及其子刊14篇，他引23000余次。筹划建立了清华大学“先进力学与材料研究中心”和浙江大学“软物质研究中心”并担任主任，引领了国内可延展无机电子器件的发展。

报告摘要：

Continuous monitoring of blood pressure, an essential measure of health status, typically requires complex, costly, and invasive techniques that can expose patients to risks of complications. Continuous, cuffless, and noninvasive blood pressure monitoring methods that correlate measured pulse wave velocity (PWV) to the blood pressure via the Moens−Korteweg (MK) and Hughes Equations, offer promising alternatives. The MK Equation, however, involves two assumptions that do not hold for human arteries, and the Hughes Equation is empirical, without any theoretical basis. The results presented here establish a relation between the blood pressure P and PWV that does not rely on the Hughes Equation nor on the assumptions used in the MK Equation. This relation degenerates to the MK Equation under extremely low blood pressures, and it accurately captures the results of in vitro experiments using artificial blood vessels at comparatively high pressures. For human arteries, which are well characterized by the Fung hyperelastic model, a simple formula between P and PWV is established within the range of human blood pressures. This formula is validated by literature data as well as by experiments on human subjects, with applicability in the determination of blood pressure from PWV in continuous, cuffless, and noninvasive blood pressure monitoring systems.